Publications

Clinical Reference Percentiles for AI-derived Epicardial Adipose Tissue: A Multicenter Study. [Article]

Assiata Kamagate, Aakash Shanbhag, Mikolaj Buchwald, Robert Jack Henry Miller, Shaun Khanna, Tara Zuhair Kassem, Jacek Kwiecinski, Renee Bullock-Palmer, Wenhao Zhang, Anna M. Marcinkiewicz, Jirong Yi, Giselle Ramirez, Mark Lemley, Aditya Killekar, Paul B. Kavanagh, Joanna X. Liang, Leandro Slipczuk, Mark I. Travin, Erick Alexanderson, Isabel Carvajal-Juarez, Rene R. S. Packard, Mouaz Al-Mallah, Terrence D. Ruddy, Robert A. deKemp, Ronny R. Buechel, Andrew J. Einstein, Wanda Acampa, Stacey Knight, Viet T. Le, Steve Mason, Thomas L. Rosamond, Edward J. Miller, Panithaya Chareonthaitawee, Daniel S. Berman, Damini Dey, Marcelo F. Di Carli, Piotr Slomka.

medRxiv (2026).

polyDAG: polynomial acyclicity constraints for efficient continuous causal discovery in visual semantic graphs. [Article] [Code]

Wenhao Zhang, Ramin Ramezani, Tao Han, Kai Hwang, Minyi Guo.

The Visual Computer (2026).

Automated AI-Based Aortic Measurements From Attenuation Correction CT as an Adjunctive Cardiovascular Risk Biomarker: An International Multicenter Study. [Article]

Anna M. Marcinkiewicz, Aakash Shanbhag, Panithaya Chareonthaitawee, Wenhao Zhang, Hasanian Al-Jilaihawi, Ryan Zaid, Sebastien Cadet, Giselle Ramirez, Mark Lemley, Jirong Yi, Waseem Hijazi, Valerie Builoff, Joanna X. Liang, Vinicius F. Calsavara, Andrew J. Einstein, Edward J. Miller, Attila Feher, Terrence D. Ruddy, Viet T. Le, Steve Mason, Stacey Knight, Erick Alexanderson, Isabel Carvajal-Juarez, Leandro Slipczuk, Mark I. Travin, Thomas L. Rosamond, Samuel B. Wopperer, Daniel S. Berman, Damini Dey, Marcelo F. Di Carli, Robert J. H. Miller, Piotr J. Slomka.

Circulation: Cardiovascular Imaging (2026).

Population-Specific Characteristics of Epicardial Adipose Tissue in Patients Undergoing Hybrid Perfusion Imaging: An AI-enabled Multicenter Study. [Article]

Assiata Kamagate, Aakash Shanbhag, Mikolaj Buchwald, Robert Miller, Wenhao Zhang, Anna Michalowska, Giselle Ramirez, Mark Lemley, Aditya Killekar, Paul Kavanagh, Joanna Liang, Leandro Slipczuk, Mark Travin, Isabel Carvajal, Rene Packard, Terrence Ruddy, Ronny Buechel, Andrew Einstein, Wanda Acampa, Stacey Knight, Viet Le, Steve Mason, Thomas Rosamond, Edward Miller, Samuel Wopperer, Panithaya Chareonthaitawee, Daniel Berman, Damini Dey, Piotr Slomka.

Journal of Nuclear Medicine (2026).

Multicenter evaluation of interpretable AI for coronary artery disease diagnosis from PET biomarkers. [PDF] [Code]

Wenhao Zhang, Jacek Kwiecinski, Aakash Shanbhag, Robert J. H. Miller, Shiva Mostafavi, Giselle Ramirez, Jirong Yi, Donghee Han, Damini Dey, Dominika Grodecka, Kajetan Grodecki, Mark Lemley, Paul Kavanagh, Joanna X. Liang, Jianhang Zhou, Valerie Builoff, Jon Hainer, Sylvain Carre, Leanne Barrett, Andrew J. Einstein, Stacey Knight, Steve Mason, Viet T. Le, Wanda Acampa, Samuel Wopperer, Panithaya Chareonthaitawee, Daniel S. Berman, Marcelo F. Di Carli, Piotr J. Slomka.

npj Digital Medicine (2026).

AI-based Aortic Measurements from Cardiac CT Attenuation Scans Identify High-risk Patients. [Article]

Aakash D. Shanbhag, Anna Marcinkiewicz, Wenhao Zhang, Ryan Zaid, Sebastien Cadet, Mark Lemley, Jirong Yi, Waseem Hijazi, Andrew J. Einstein, Edward J. Miller, Attila Feher, Terrence D. Ruddy, Viet Le, Steve Mason, Stacey Knight, Leandro Slipczuk, Mark Travin, Thomas Rosamond, Samuel Wopperer, Panithaya Chareonthaitawee, Daniel S. Berman, Damini Dey, Marcelo F. Di Carli, Robert J. H. Miller, Piotr J. Slomka.

Journal of Nuclear Cardiology (2025).

AI-based hepatic steatosis detection and integrated hepatic assessment from cardiac CT attenuation scans enhances all-cause mortality risk stratification: a multi-center study. [Article]

Jirong Yi, Krishna K. Patel, Robert J. H. Miller, Anna M. Marcinkiewicz, Aakash Shanbhag, Waseem Hijazi, Naga Dharmavaram, Mark Lemley, Jianhang Zhou, Wenhao Zhang, Joanna X. Liang, Giselle Ramirez, Valerie Builoff, Leandro Slipczuk, Mark Travin, Erick Alexanderson, Isabel Carvajal-Juarez, René R. S. Packard, Mouaz Al-Mallah, Terrence D. Ruddy, Andrew J. Einstein, Attila Feher, Edward J. Miller, Wanda Acampa, Stacey Knight, Viet T. Le, Steve Mason, Vinicius F. Calsavara, Panithaya Chareonthaitawee, Samuel Wopperer, Alan Kwan, Lixia Wang, Daniel S. Berman, Damini Dey, Marcelo Di Carli, Piotr J. Slomka.

medRxiv (2025).

AI-based identification of patients who benefit from revascularization: a multicenter study. [Article]

Wenhao Zhang, Robert J. H. Miller, Krishna Patel, Aakash D. Shanbhag, Joanna X. Liang, Mark Lemley, Giselle Ramirez, Valerie Builoff, Jirong Yi, Jianhang Zhou, Paul Kavanagh, Wanda Acampa, Timothy M. Bateman, Marcelo Di Carli, Sharmila Dorbala, Andrew J. Einstein, Mathews B. Fish, M. Timothy Hauser, Terrence D. Ruddy, Philipp A. Kaufmann, Edward J. Miller, Tali Sharir, Monica Martins, Julian Halcox, Panithaya Chareonthaitawee, Damini Dey, Daniel S. Berman, Piotr J. Slomka.

medRxiv (2025).

82Rb positron emission tomography myocardial blood flow quantification: Influence of arterial input curve quality on diagnostic accuracy. [Article]

Hidesato Fujito, Mark Lemley, Valerie Builoff, Wenhao Zhang, Keiichiro Kuronuma, Giselle Ramirez, Aditya Killekar, Joanna X. Liang, Paul Kavanagh, Mark C. Hyun, Sean W. Hayes, Louise E. J. Thomson, John D. Friedman, Serge D. Van Kriekinge, Marcelo F. Di Carli, Damini Dey, Daniel S. Berman, Piotr J. Slomka.

Journal of Nuclear Cardiology (2025).

AI-based integrated body composition assessment from cardiac SPECT CT attenuation maps and its association with mortality. [Article]

Jirong Yi, Krishna Patel, Anna Michalowska, Aakash Shanbhag, Robert Miller, Wenhao Zhang, Aditya Killekar, Mark Lemley, Jianhang Zhou, Joanna Liang, Giselle Ramirez, Valerie Builoff, Terrence Ruddy, Andrew Einstein, Attila Feher, Edward Miller, Daniel Berman, Damini Dey, Piotr Slomka.

Journal of Nuclear Medicine (2025).

AI-based volumetric six-tissue body composition quantification from CT cardiac attenuation scans for mortality prediction: a multicentre study. [Article]

Jirong Yi, Anna M. Marcinkiewicz, Aakash Shanbhag, Robert J. H. Miller, Jolien Geers, Wenhao Zhang, Aditya Killekar, Nipun Manral, Mark Lemley, Mikolaj Buchwald, Jacek Kwiecinski, Jianhang Zhou, Paul B. Kavanagh, Joanna X. Liang, Valerie Builoff, Terrence D. Ruddy, Andrew J. Einstein, Attila Feher, Edward J. Miller, Albert J. Sinusas, Daniel S. Berman, Damini Dey, Piotr J. Slomka.

The Lancet Digital Health (2025).

Deep learning-enabled, computed-tomography-based race-and sex-specific epicardial adipose tissue thresholds for cardiovascular risk stratification. [Article]

Mikolaj Buchwald, Aakash Shanbhag, Robert J. H. Miller, Wenhao Zhang, Anna M. Michalowska, Aditya Killekar, Mark Lemley, Paul B. Kavanagh, Hidesato Fujito, Joanna X. Liang, Valerie Builoff, Stacey Knight, Andrew J. Einstein, Edward J. Miller, Attila Feher, Albert J. Sinusas, Panithaya Chareonthaitawee, Renee P. Bullock-Palmer, Marcelo F. Di Carli, Daniel S. Berman, Damini Dey, Piotr J. Slomka.

Medical Imaging 2025: Clinical and Biomedical Imaging (2025).

Holistic AI analysis of hybrid cardiac perfusion images for mortality prediction. [PDF] [Code]

Anna M. Marcinkiewicz, Wenhao Zhang, Aakash Shanbhag, Robert J. H. Miller, Mark Lemley, Giselle Ramirez, Mikolaj Buchwald, Aditya Killekar, Paul B. Kavanagh, Attila Feher, Edward J. Miller, Andrew J. Einstein, Terrence D. Ruddy, Joanna X. Liang, Valerie Builoff, David Ouyang, Daniel S. Berman, Damini Dey, Piotr J. Slomka.

npj Digital Medicine (2025).

Automated proximal coronary artery calcium identification using artificial intelligence: advancing cardiovascular risk assessment. [Article]

Jianhang Zhou, Aakash D. Shanbhag, Donghee Han, Anna M. Marcinkiewicz, Mikolaj Buchwald, Robert J. H. Miller, Aditya Killekar, Nipun Manral, Kajetan Grodecki, Jolien Geers, Konrad Pieszko, Jirong Yi, Wenhao Zhang, Parker Waechter, Heidi Gransar, Damini Dey, Daniel S. Berman, Piotr J. Slomka.

European Heart Journal—Cardiovascular Imaging (2025).

Developing remote patient monitoring infrastructure using commercially available cloud platforms. [Article]

Minh Cao, Ramin Ramezani, Vivek Kumar Katakwar, Wenhao Zhang, Dheeraj Boda, Muneeb Wani, Arash Naeim.

Frontiers in Digital Health (2024).

Remote patient monitoring for global emergencies: a case study in COVID-19 patients. [PDF]

Ramin Ramezani, Wenhao Zhang, Minh Cao, Alex Bui, Antonia Petruse, Amelia Weldon, Arash Naeim.

Preprints (2024).

Enhanced Risk Prediction for Cardiac PET/CT Using Cardiac Chamber Volumes and Myocardial Mass Derived From CT Attenuation Maps Using Deep Learning. [Article]

Aakash D. Shanbhag, Robert Miller, Wenhao Zhang, Mark Lemley, Giselle Ramirez, Damini Dey, Daniel S. Berman, Marcelo F. Di Carli, Piotr J. Slomka.

Journal of Nuclear Cardiology (2024).

Automating Revascularization Decision Support: Clinical Application of Artificial Intelligence. [PDF]

Wenhao Zhang, Robert J. H. Miller, Krishna K. Patel, Aakash Shanbhag, Joanna X. Liang, Marcelo F. Di Carli, Sharmila Dorbala, Andrew J. Einstein, Mathews Fish, M. Timothy Hauser, Philipp A. Kaufmann, Edward J. Miller, Terrence D. Ruddy, Timothy M. Bateman, Monica Martins, Tali Sharir, Julian Halcox, Wanda Acampa, Damini Dey, Daniel Berman, Piotr Slomka.

Journal of Nuclear Cardiology (2024).

Fully automated aortic diameter measurements on SPECT/CT attenuation maps in patients undergoing myocardial perfusion imaging. [Article]

Aakash Shanbhag, Anna Michalowska, Wenhao Zhang, Robert J. H. Miller, Mark Lemley, Andrew Einstein, Joanna Liang, Valerie Builoff, Daniel Berman, Damini Dey, Piotr Slomka.

European Heart Journal—Cardiovascular Imaging (2024).

AI detects patient race from myocardial perfusion PET: towards understanding unintended biases of predictive models. [Article]

Mikolaj Buchwald, Aakash Shanbhag, Robert Miller, Wenhao Zhang, Anna Michalowska, Aditya Killekar, Mark Lemley, Paul Kavanagh, Hidesato Fujito, Joanna Liang, Valerie Builoff, Daniel Berman, Damini Dey, Piotr Slomka.

Journal of Nuclear Medicine (2024).

AI-derived multi-structure analysis from cardiac SPECT/CT attenuation maps improves mortality prediction from myocardial perfusion imaging. [Article]

Anna Michalowska, Wenhao Zhang, Aakash Shanbhag, Robert Miller, Mikolaj Buchwald, Bryan Bednarski, Aditya Killekar, Mark Lemley, Paul Kavanagh, Konrad Pieszko, Attila Feher, Edward Miller, Andrew Einstein, Terrence Ruddy, Joanna Liang, Valerie Builoff, Daniel Berman, Damini Dey, Piotr Slomka.

Journal of Nuclear Medicine (2024).

AI-based approach to improve coronary artery disease diagnosis from cardiac PET. [Article]

Wenhao Zhang, Hidesato Fujito, Aakash Shanbhag, Jirong Yi, Robert Miller, Mikolaj Buchwald, Mark Lemley, Paul Kavanagh, Joanna Liang, Jianhang Zhou, Bryan Bednarski, Valerie Builoff, Marcelo F. Di Carli, Damini Dey, Daniel Berman, Piotr Slomka.

Journal of Nuclear Medicine (2024).

Volumetric assessment of body composition from cardiac SPECT CT attenuation maps and association of sarcopenia measures with mortality. [Article]

Jirong Yi, Anna Michalowska, Aakash Shanbhag, Robert Miller, Wenhao Zhang, Aditya Killekar, Nipun Manral, Mark Lemley, Jianhang Zhou, Bryan Bednarski, Joanna Liang, Valerie Builoff, Terrence Ruddy, Andrew Einstein, Attila Feher, Edward Miller, Albert Sinusas, Paul Kavanagh, Damini Dey, Daniel Berman, Piotr Slomka.

Journal of Nuclear Medicine (2024).

Effect of stress/rest peak ratio of the arterial input curves on diagnostic performance of 82Rb PET myocardial blood flow quantification. [Article]

Hidesato Fujito, Wenhao Zhang, Mark Lemley, Keiichiro Kuronuma, Aditya Killekar, Valerie Builoff, Paul Kavanagh, Mark Hyun, Sean Hayes, Louise Thomson, John Friedman, Serge Van Kriekinge, Marcelo F. Di Carli, Damini Dey, Daniel Berman, Piotr Slomka.

Journal of Nuclear Medicine (2024).

ECG Heartbeat classification using deep transfer learning with Convolutional Neural Network and STFT technique. [PDF] [Code]

Minh Cao, Tianqi Zhao, Yanxun Li, Wenhao Zhang, Peyman Benharash, Ramin Ramezani.

Journal of Physics: Conference Series (2023).

Towards Fair and Interpretable AI Healthcare Predictive Models: From Wearable Sensors to Causal Graphs. [Article]

Wenhao Zhang.

Ph.D. dissertation, University of California, Los Angeles (2023).

Temporal convolutional networks and data rebalancing for clinical length of stay and mortality prediction. [Article]

Bryan P. Bednarski, Akash Deep Singh, Wenhao Zhang, William M. Jones, Arash Naeim, Ramin Ramezani.

Scientific Reports (2022).

Range of motion sensors for monitoring recovery of total knee arthroplasty. [Article]

Minh Cao, Brett Bailey, Wenhao Zhang, Solana Fernandez, Aaron Han, Smiti Narayanan, Shrineel Patel, Steven Saletta, Alexandra Stavrakis, Stephen Speicher, Stephanie Seidlits, Arash Naeim, Ramin Ramezani.

IEEE-EMBS International Conference on Wearable and Implantable Body Sensor Networks (2022).

Physical activity behavior of patients at a skilled nursing facility: longitudinal cohort study. [Article]

Ramin Ramezani, Wenhao Zhang, Pamela Roberts, John Shen, David Elashoff, Zhuoer Xie, Annette Stanton, Michelle Eslami, Neil S. Wenger, Jacqueline Trent, Antonia Petruse, Amelia Weldon, Andy Ascencio, Majid Sarrafzadeh, Arash Naeim.

JMIR mHealth and uHealth (2022).

The derivation of an International Classification of Diseases, Tenth Revision–based trauma-related mortality model using machine learning. [Article]

Zachary Tran, Wenhao Zhang, Arjun Verma, Alan Cook, Dennis Kim, Sigrid Burruss, Ramin Ramezani, Peyman Benharash.

Journal of Trauma and Acute Care Surgery (2022).

Causal inference in medicine and in health policy: A summary. [Article]

Wenhao Zhang, Ramin Ramezani, Arash Naeim.

Handbook on Computer Learning and Intelligence, Volume 2 (2022).

A pilot study of a wearable monitoring system as an adjunct to geriatric assessment in older adults with cancer. [Article]

Karlton Wong, John Shen, Ramin Ramezani, Wenhao Zhang, Zhuoer Xie, Arash Naeim, David Elashoff.

Journal of Clinical Oncology (2020).

Large-scale causal approaches to debiasing post-click conversion rate estimation with multi-task learning. [PDF]

Wenhao Zhang, Wentian Bao, Xiao-Yang Liu, Keping Yang, Quan Lin, Hong Wen, Ramin Ramezani.

The Web Conference (2020).

WOTBoost: Weighted oversampling technique in boosting for imbalanced learning. [Article]

Wenhao Zhang, Ramin Ramezani, Arash Naeim.

IEEE International Conference on Big Data (2019).

GenSample: a genetic algorithm for oversampling in imbalanced datasets. [PDF]

Vishwa Karia, Wenhao Zhang, Arash Naeim, Ramin Ramezani.

arXiv (2019).

A combination of indoor localization and wearable sensor–based physical activity recognition to assess older patients undergoing subacute rehabilitation: Baseline study results. [Article]

Ramin Ramezani, Wenhao Zhang, Zhuoer Xie, John Shen, David Elashoff, Pamela Roberts, Annette Stanton, Michelle Eslami, Neil Wenger, Majid Sarrafzadeh, Arash Naeim.

JMIR mHealth and uHealth (2019).

Using Smart Watch Sensing in At-Risk Populations (SARP) in a Sub-Acute Rehabilitation Center. [Article]

Zhuoer Xie, Ramin Ramezani, David Elashoff, Pamela Roberts, John Shen, Wenhao Zhang, Michelle Eslami, Arash Naeim.

Archives of Physical Medicine and Rehabilitation (2018).